IDH mutation

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Prognostic role of IDH mutations in gliomas: a meta-analysis of 55 ...2015年7月16日 · IDH (Isocitrate dehydrogenase) mutations occur frequently in gliomas, but ... Castiglione F, Degl'Innocenti DR, Gheri CF, Genitori L, Taddei GL.Consequences of IDH1/2 Mutations in Gliomas and an Assessment ...2019年3月9日 · IDH mutations occur early in pathogenesis of gliomas and persist ... Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.M., Gallia G.L., et al.The prognostic role of IDH mutations in homogeneously treated ...2019年10月17日 · The detection of IDH mutations in patients with diffusely infiltrating ... Instead, patients with an AA and an IDH mutation receiving the same therapy had a mOS of 54 months. Thus ... Gallia GL, Giovanella BC et al (2013) TERT promoter mutations ... BMC Twitter page · BMC Facebook page · BMC Weibo page.Mutant IDH1 confers resistance to energy stress in normal biliary ...2019年12月11日 · Although mutant IDH can be detected even in the early stages of ... Tyson, G. L. & El‐Serag, H. B. Risk factors for cholangiocarcinoma. ... Cairns, R. A. & Mak, T. W. Oncogenic Isocitrate Dehydrogenase Mutations: Mechanisms, ...Isocitrate dehydrogenase mutations in myeloid malignancies - Nature2016年10月10日 · Recurring mutations in isocitrate dehydrogenase (IDH) genes are detected in approximately ... The prognostic significance of mutant IDH (mIDH) is controversial but appears to be influenced ... Cairns RA, Harris IS, Mak TW . ... Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.IDH Mutation Analysis in Glioma Patients by CADMA Compared with ...2018年3月19日 · Mutations in IDH1/2 genes are a marker of good prognosis for glioma patients, ... Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, ... Cairns RA, Mak TW (2013) Oncogenic isocitrate dehydrogenase ...Roles of IDH1/2 and TET2 mutations in myeloid disorders ...2016年3月15日 · Mutations of the epigenetic enzymes isocitrate dehydrogenase (IDH) ... Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine ... Wang C, McKeithan TW, Gong Q, Zhang W, Bouska A, Rosenwald A, et al ...Isocitrate dehydrogenase mutations in gliomas | Neuro-Oncology ...2015年7月16日 · Isocitrate dehydrogenase (IDH) enzymes catalyze the oxidative ... and others have now shown that IDH mutations occur in the vast majority ... TW . Oncogenic isocitrate dehydrogenase mutations: mechanisms, ... Semenza. GL . Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases.Detection of IDH1 and IDH2 Mutations by Fluorescence Melting ...Novel mutations in the isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) genes ... and 5′-ATCCCCATAAGCATGACGACCTA-FL-3′) were used to generate a ...What a difference a hydroxyl makes: mutant IDH, (R)-2 ...Cancer-associated IDH mutations alter the enzymes such that they reduce 2OG to the ... The third mutated enzyme, isocitrate dehydrogenase (IDH), is a more complicated case. ... Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G, Butler A, Davies H, Edkins S, Hardy C, Latimer C, et al. 2010. ... Reddit; Add to Twitter ...


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